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Please use this identifier to cite or link to this item: http://hdl.handle.net/2239/33840

Title: Zinc absorption in Guatemalan schoolchildren fed normal or low-phytate maize.
Authors: Mazariegos, Manolo
Hambidge, K Michael
Krebs, Nancy F
Westcott, Jamie E
Lei, Sian
Grunwald, Gary K
Campos, Raquel
Barahona, Brenda
Raboy, Victor
Solomons, Noel W
USDA, ARS
Keywords: nutrition assessment
child nutrition
school children
nutrient deficiencies
zinc
dietary minerals
corn
phytin
mineral metabolism
nutrient availability
intestinal absorption
long term effects
nutritional status
stable isotopes
Guatemala
Issue Date: 17-Oct-2007
Description: BACKGROUND: Poor bioavailability of zinc from high-phytate diets is an important contributory factor to zinc deficiency in low-income populations. OBJECTIVE: The objective of this study was to determine the effect of low-phytate maize consumption on zinc absorption. DESIGN: The participants were apparently healthy children from the Central Highlands of Guatemala. Sixty children (20 per group) were randomly assigned to be fed only the low-phytate maize or 1 of 2 control maizes, the isohybrid wild-type maize or a local maize, for a 10-wk period. During the final week, the fractional absorption of zinc for all meals was measured during 1 d with the use of zinc stable isotopes and a dual isotope ratio technique based on urine enrichment data. RESULTS: Mean (±SD) phytate intakes for the low-phytate, wild-type, and local maize groups were 1536 ± 563, 2056 ± 517, and 2253 ± 687 mg/d, respectively. Corresponding zinc intakes were 8.6 ± 2.5, 8.1 ± 2.0, and 9.7 ± 2.6 mg/d, and the dietary phytate:zinc molar ratios were 18 ± 5, 26 ± 6, and 23 ± 5. Corresponding fractional absorptions of zinc were 0.32 ± 0.07, 0.28 ± 0.07, and 0.29 ± 0.06. The respective values for total absorbed zinc were 2.72 ± 0.88, 2.30 ± 0.96, and 2.78 ± 1.04 mg/d. No significant differences in either the fractional absorption of zinc or total absorbed zinc were seen between the maize groups. CONCLUSION: Under the conditions of the present study, zinc absorption was not increased by the long-term use of low-phytate maize in children whose major dietary staple is maize.
URI: http://seekspace.resip.ac.cn/handle/2239/33840
Other Identifiers: http://seekspace.resip.ac.cn/handle/10113/2058
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